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Microbial diversity is fundamental to maintaining gut ecosystem homeostasis and overall host health, with its abundance and stability directly shaping the adaptability of the intestinal microecosystem and host physiological function

For the shRNA KD ChIP-seq data sequenced by Novogene, the raw sequencing reads were trimmed by Cutadapt and then mapped by Bowtie 2 with the --very-sensitive parameter

To better understand how changes in intracellular GSH metabolism might contribute to the expansion, survival, and function of CD8 + T cells upon chronic antigenic stimulation, we used an in vitro system (26) whereby activated transgenic or wild-type (WT) T cells were expanded in the presence of persistent antigenic stimulation with either specific antigen (OVA-I/gp100) or anti-CD3mediated stimulation and anti-CD28 costimulation for 7 days

T-REX coupled with co-immunoprecipitation assays revealed that NCBP1-HNEylation caused no perturbation of the association between NCBP1 and ALYREF, PHAX or PRPF4 (Supplementary Fig

Inhibiting aerobic glycolysis suppresses renal interstitial fibroblast activation and renal fibrosis