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Overtraining, however, can suppress GH axis function and potentially limit sermorelin's effectiveness

However, our findings challenge this notion, instead revealing potential limitations that must be addressed to advance more effective therapies

Off-Label Use in Wellness and Aesthetics Beyond its FDA-approved indication, tesamorelin is often used in medspa and regenerative medicine settings for: Reducing abdominal or visceral fat Preserving lean muscle mass Enhancing recovery and metabolism In these wellness applications, the 2 mg daily dose typically remains standard, though some providers modify schedules, such as 5 days on and 2 days off, to align with patient goals

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doi:10.3389/fgene.2017.00213