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monitor patients for the emergence or worsening of depression, suicidal thoughts or behavior, and any unusual changes in moods or behaviors

Standard treatment protocols involve twice-weekly injections for 4-6 weeks, followed by maintenance therapy tailored to individual response and deficiency severity

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Simultaneously, nicotinamide is consumed reducing the substrate available for the salvage pathway to regenerate NAD+

While there is some uncertainty, consult a health professional for suitability and safety