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[74] found that FA-binding protein 5 interacts with FASN, positively regulating its expression through the ubiquitinproteasome pathway, which activates the Wnt/-catenin signaling pathway and promotes lipid metabolism, playing a critical role in the progression of pancreatic neuroendocrine tumors

For example, eight Australian families with Lebanese ancestry diagnosed with LS or LS-like encephalopathy associated with COX deficiency had mutations in the PET100 gene (Lim et al., 2014)

H.MeyerA

Cell death by ferroptosis is genetically prevented by the lipid repair enzyme glutathione peroxidase 4 (GPX4), which converts lipid hydroperoxides to unreactive lipid alcohols [17]

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