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International Journal of Biomedical Science : IJBS, 11(2), 54

GaultierAArandjelovicSNiessenSOvertonCDLintonMFFazioSet alRegulation of tumor necrosis factor receptor-1 and the IKK-NF-kappaB pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptor

Grx2 knockout or overexpression exacerbates or diminishes lipid peroxidation in human lens epithelial cells or opacity in mouse lenses, respectively, after treatment with ferroptosis inducers or UV-B via modulation of mitochondrial structure and the GSH/GSSG ratio [128]

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Products containing Glutathione or Vitamin A derivatives require more careful use protocols, potentially limiting frequency to 3 to 4 times weekly in sensitive skin types to minimize irritation risk