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Wu et al., 2016) and downregulates miR375 (Ladeiro et al., 2008)

Japan and Italys populations have the highest measured ERGO levels in their blood Countries that have a high human intake of ERGO-containing mushrooms in their diet have measured blood levels of ERGO much higher than countries where mushrooms are not a part of their daily cuisine (2), as outlined below: Japan 6.6 mg/day ERGO Italy 4.6 mg/day ERGO France 2.2 mg/day ERGO Finland 1.3 mg/day ERGO United States 1.1 mg/day ERGO Of note is the fact that Japan and Italy also have some of the highest life expectancies and lower chronic disease rates compared to other first-world countries

Heidet 2009)

doi:10.1002/art.41882

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