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Contrary to our findings, the result of an RCT that evaluated the effect of adding L-carnitine to clomiphene citrate on pregnancy outcome in ovarian stimulation and IUI cycles showed improvement in ovulation and cumulative pregnancy rates in clomiphene-resistant women with PCOS

It plays a crucial role in the transport of long-chain fatty acids into the mitochondria, where they are oxidized to produce energy

Carnitine is an amino acid derivative (a building block of protein) made by the body in the liver, kidneys and brain, from two other amino acids, lysine and methionine

Carnitine finely regulates the metabolic pathway through fatty acid transport

After induction of the hypertone and parallel treatment with carnitine, the expression of this marker of glial cells is significantly reduced (Figure 1a, 2)