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Bulletin of Experimental Biology and Medicine

In vivo serum pharmacokinetic and organ distribution Serum pharmacokinetics were determined after application of a single dose of oxaliplatin (9 mg/kg) as compared to BSO-OxMal at the equimolar dose (23.5 mg/kg) in tumor-free, male BALB/c mice ( n = 4/experimental group)

The reduction of dehydroascorbate may be non-enzymatic or catalysed by proteins with dehydroascorbate reductase activity, such as glutathione S -transferase omega 1 or glutaredoxins

By day 3, the no-Cys and no-Trp + BSO diets resulted in approximately 20% and 18% weight loss, respectively, in Cse / mice

However, translating native bilirubin into clinical therapy faces pharmacological challenges