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Second, informative injury models need to mimic the injuries seen in sporting environments (Wall and Shani, 2008), yet most brain injury models create focal hemorrhagic cortical lesions caused by direct impact to the skull or exposed brain (Xiong et al., 2013), while the human concussed brain is more commonly associated with distributed white matter alterations (Benson et al., 2007

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The answer appears to lie in gene expression changes that create self-sustaining repair programs

Safety Considerations and Side Effects BPC-157 demonstrates a favorable safety profile across animal studies and extensive anecdotal human use

Russian State Register of Medicines (in Russian)