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Among the subtypes, ER+/HER2, which is the least aggressive, had the lowest level of infiltrating M1, whereas triple negative (TN), the most aggressive subtype, demonstrated the highest level (Fig

Evidencing changes indicate the possibility of prebiotics having neuroprotective, stress-buffering effects through the modulation of the MGBA by restoring microbial homeostasis, changing neuroendocrine responses, or affecting gene expression in stress-related brain regions (Burokas et al., 2017)