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Disclosures: Liam Swain: Nothing to Disclose, Jenny Godley: Nothing to Disclose, Meng Wang: Nothing to Disclose, Jennifer Flemming: Nothing to Disclose, Mayur Brahmania: Nothing to Disclose, Juan Abraldes: Gilead: Grant/Research Support, 89bio: Consultant, Boston Pharmaceuticals: Consultant, Novo Nordisk: Consultant, Boehringer Ingelheim: Consultant, Astra Zeneca: Consultant, Agomab: Consultant, Terumo: Speaking and Teaching, Cook: Grant/Research Support, Karen Tang: Nothing to Disclose, Abdel Shaheen: Nothing to Disclose 1549 THE EFFECT OF AREA-LEVEL MATERIAL AND SOCIAL DEPRIVATION ON CIRRHOSIS AND ALCOHOL-RELATED HEPATITIS HOSPITALIZATION RATES DURING THE COVID-19 PANDEMIC: A POPULATION-BASED STUDY Liam Swain Abdel Shaheen 1 Meng Wang 2 Jennifer Flemming 3 Mayur Brahmania 1 Juan Abraldes 4 Karen Tang 1 Jenny Godley 1 , 1 University of Calgary, 2 Alberta Health Services, 3 Queen's University Cancer Research Institute, 4 University of Alberta Background: Few studies have examined the impact of the COVID-19 pandemic on hospitalization rates for alcohol-related cirrhosis/hepatitis (AC/AH) and non-alcohol-related cirrhosis (NAC) in relation to the social determinants of health

Similarly, inhibition of mTOR reduces the levels of glycine, asparagine, glutamine, and proline, all of which are essential for fibroblast activation and matrix deposition [111]

Detoxifies the Body: Glutathione supports the liver in removing toxins, heavy metals, and harmful chemicals

15 , a041237 (2023)