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376,377 Although some evidence points to a Gq/11-like extralarge G protein (GXL)-IP3-PKC pathway in FGF23 induction, 378 its role in LPA signaling remains unclear

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Emerging platforms, such as gold nanoparticles or bioreducible lipid nanoparticles, further enhance this synergy by facilitating endosomal escape and intracellular release of Cas9-sgRNA ribonucleoproteins (RNPs) [310]

3a), but without the assembly of the DNA libraries onto NCPs