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Based on a multivariate analysis, peak blood lactate concentration was the only factor independently associated with L-carnitine administration (odds ratio, 1.9, 95% confidence interval, 1.22.8

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Given this complex picture, although mitochondrial dysfunction, suggested by a number of studies [60], is a plausible reason for lactate elevations in ME/CFS, the other possibilities should not be discarded

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Owners should be advised that ventricular antiarrhythmics have the potential for proarrhythmic effects and that treatment is not known to decrease risk of sudden death