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Although O 2 - per se is not highly reactive, it becomes reactive when it interacts with transition metal complexes of iron, copper and manganese leading to increased oxidative stress [82,83]

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5(10): p

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Abstract The endocannabinoid system (ECS) is composed of the endocannabinoid ligands anandamide (AEA) and 2-arachidonoylgycerol (2-AG), their target cannabinoid receptors (CB 1 and CB 2 ) and the enzymes involved in their synthesis and metabolism ( N -acyltransferase and fatty acid amide hydrolase (FAAH) in the case of AEA and diacylglycerol lipase (DAGL) and monoacylglycerol lipase (MAGL) in the case of 2-AG)

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