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They try to power through it

Sunil Kumar BV, Singh S, Verma R (2017) Anticancer potential of dietary vitamin D and ascorbic acid: a review

Diagnosis and treatment of alcohol-associated liver diseases: 2019 practice guidance from the American Association for the study of liver diseases

Bertini et al

The principle of the maintenance immunosuppression is regarding lifelong inhibition of immune cells activation and proliferation, such as the calcineurin inhibitor (tacrolimus) used in the Edmonton protocol, with the clear disadvantage that most of these agents show liver/kidney toxicity and have direct toxicity to cells