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Similarly, DUSP1 mRNA levels are also decreased in bronchial epithelial cells of allergic rhinitis and asthma patients [123]

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Together these data indicate that the 6-AH family of AngIV analogs exert their biological activity by modifying the activity of the HGF/Met system and offer the potential as therapeutic agents in disorders that are dependent on or possess an over-activation of the HGF/Met system