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Enzyme Inhib

Battaglini M, et al

Biochim Biophys Acta 2016;1857:1147-57

Combined treatment with DFX-DFO rapidly reduces myocardial and hepatic iron concentrations and significantly improves myocardial function and ejection fraction in patients with severe transfusional myocardial siderosis (NCT01254227)

Prokineticin is a group of chemokines that promote the release of pro-inflammatory and pro-nociceptive mediators, and are also involved in the epigenetic regulation of genes related to cell differentiation