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Like photoreceptors and ganglion cells, the role of Nrf2 for protection against phototoxic stress in RPE cells has been examined with in vitro studies demonstrating that sulforaphane, an Nrf2 activator can protect RPE cells from blue light-induced damage (Sternberg et al., 1993

One PBNP system, coated with erythrocyte membranes, inhibits and depolymerizes A aggregates via photothermal effects

Furthermore, because CoQ10 acts as a remarkably potent, lipid-soluble antioxidant, increasing its concentration within the mitochondrial membrane provides a robust shield against cellular damage

Exposure to environmental pollution and poor sleep can also deplete levels further

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