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2022;14:1677.ArticlePubMedPMC 20

Follow-up data in older patients demonstrate that the joint hypermobility becomes more pronounced later

Based on the considerations mentioned above, it seems reasonable that the proinflammatory cytokine IL-17 interferes with insulin signaling and insulin sensitivity (Figure 2) and contributes to adipoflammation and metaflammation in obesity and diabetes (139)