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Enhancements of dopamine bio-synthesis as estimated fi'om HVA concentration in CSF correlate withCSF tyrosine (C), Increases in the biosynthesis of dopamine and serotonin as measured by increased CSF concentrations of HVA and5-HIAA correlate with dietary tyrosine supplement (D)

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Dihexa at a glance Not approved research chemical Type Research compound not approved for human use, never tested in a clinical trial Also called N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, PNB-0408, Angiotensin IV analog Interest in it for Synapse formation, memory, and cognition in animal models of dementia Evidence Animal and lab studies only zero human trials

Our paper used the Remien model of cell death in the liver

The rationale involves complementary mechanisms