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demonstrated that gastric cancer cell lines MKN45 and SGC-7901 cultured in methionine-deficient medium exhibited significantly reduced cell viability and proliferative capacity (42)

In this study, we focused on direct modulation of the GSH biosynthetic pathway via a method of three-pathway combination

The HIF-1 response is triggered by hypoxia but is probably a defense mechanism, not only for cell survival but also for limiting viral spread since HIF-1 is shown to suppress ACE2-R and transmembrane protease serine 2 (TMPRSS2) [152]

Mitochondria-associated membrane collapse is a common pathomechanism in SIGMAR1- and SOD1-linked ALS

doi:10.21203/rs.3.rs-3385749/v1 152