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Oct 6 2022;19(19)doi:10.3390/ijerph191912762 University of California San Francisco

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In the most comprehensive pediatric meta-analysis, Contopoulos-Ioannidis et al., ( Age-specific extended-interval protocols account for developmental pharmacokinetic variability, particularly the maturational changes in GFR and volume of distribution that influence aminoglycoside clearance across gestational and postnatal age

38-41 Other than major histocompatibility complex, the two largest genome-wide association studies also identified other polymorphisms that were associated with SS