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Annals Of Surgical Oncology 2026, 33: 3407-3408

[1] The result is that the same gene can yield transcripts commonly labeled IGF-1Ea, IGF-1Eb, and IGF-1Ec, each carrying the identical mature IGF-1 core but a different tail

Key focal alterations include CDKN2A/B deletions and high-level EGFR amplifications, which contribute to tumor progression and therapy resistance