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Procyanidins exhibits neuroprotective activities against cerebral ischemia reperfusion injury by inhibiting TLR4-NLRP3 inflammasome signal pathway

Ferritin, including ferritin heavy chain 1 (FTH1) and ferritin light chain (FTL), sequesters excess intracellular iron (Zhou et al., 2024)

However, the ROS-detoxifying Nrf2 target genes, MnSOD and catalase, were eventually induced but with a significant delayed expression compared with the WT mice

Ito J., Nagayasu Y., Miura Y., et al., Astrocytes Endogenous apoE Generates HDLLike Lipoproteins Using Previously Synthesized Cholesterol Through Interaction With ABCA1, Brain Research 1570 (2014): 112

10.1038/ncomms12504 63 de BaaijJ