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The consistency of the safety profile across short-term and long-term trials suggests that AOD-9604 does not produce cumulative toxicity or delayed adverse effects that emerge only with chronic administration

Studies have shown that a deficiency in B12 can lead to neurological disorders, but supplementation, even without proven deficiency, has shown benefits in conditions like peripheral neuropathy

Abnormal homocysteine metabolism in rheumatoid arthritis

Dr Jastreboff notes that mild to moderate gastrointestinal side effects are possible

Some individuals have difficulty maintaining healthy B12 levels through diet alone, especially those following plant-based diets or experiencing absorption challenges