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445 However, this approach has been associated with high complication rates in the literature, with a reported mortality rate of 24%, and often necessitates multiple operations

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The exclusive worldwide right to commercialize the technology for the targeted delivery of drugs to the brain was acquired by to-BBB technologies BV in 2008 [40]

doi: 10.3390/ijms18081680 52 WangGAlamuriPMaierRJ

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