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Although 5-amino-1MQ has not yet been extensively studied in this context, its demonstrated ability to increase NAD+ levels in other tissues has prompted interest in exploring whether similar effects may occur in the brain

Heterogeneity was further assessed by subgroup analysis based on trial characteristics, followed by meta-regression to examine the effect of the year of publication and sample size on representativeness

Despite the fact that the ferroptosis triggered by these pathogens has not been validated in skin tissues, these studies bring new insights into the research of their respective pathogenesis and therapeutic targets (Figure 4)