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For example, -catenin interacts with the chromatin organizer special AT-rich binding protein 1 (SATB1) and mediates the expression of specific set of genes during T helper-cell differentiation (Notani et al., 2010) and colorectal cancer progression (Mir et al., 2016), presumably via alterations in chromatin domain organization (Shahbazian and Grunstein, 2007

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