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For the therapeutic intervention, GYY4137 was intraperitoneally injected into mice (50 mg/kg body weight) every other day for 8 weeks one day after surgery, while control animals

Mitochondria are also involved in key cellular functions such as Ca 2 + homeostasis, heme biosynthesis, nutrient metabolism (Cheng and Ristow, 2013), steroid hormone biosynthesis, removal of ammonia, integration of metabolic and signaling pathways for cell death and autophagy (Hammerman et al., 2004

Lastly, thiolase cleaves 3-ketoacyl coenzyme-A to produce a two-carbon chain shortened Acyl-Coenzyme A and Acetyl-Coenzyme A

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