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Figure 4a showed that rhGPx3 mutant was superimposed on U46C GPx4 mutant (PDB entry 2OBI) with a root mean square deviation of 2.87 , for 156 C-Alpha atoms

On the other hand, treatment with l-carnitine (200 mg/kg/day) for 28 successive days showed non-significant change in ACC2 protein level, but significantly increased mRNA expression by 101% in rat heart tissues as compared to the control

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Conclusion We designed and synthesised an iron-based MOF nanoplatform BSO@MOF-L, which not only contained enough iron but also loaded a high dose of BSO