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However, for simplicity, throughout this manuscript variants will be identified only by alteration of the specific residue under study, excluding reference to the U597C mutation

Gut dysbiosis may thus result in deficiencies of critical micronutrients, notably iodine, selenium, iron, zinc, and vitamin D, which are indispensable for optimal thyroid function and regulation (Knezevic et al., 2020)

Astrocytes can participate in neurotransmission by regulating ion concentrations and neurotransmitters (Tritsch and Bergles, 2007)

These medications are being investigated as a potential treatment modality for COVID-19 [5]