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Description

R., Queiroz-Junior, C

70 LabianoS.PalazonA.MeleroI

Counteracts Myostatin Levels: Elevated levels of the myostatin protein can slow or completely inhibit new muscle growth

For the ARISTOTLE trial population (apixaban for AF), the dose-reduction criteria require 2.5 mg twice daily when two or more of the following are present: age 80 years or older, body weight 60 kg or less, or serum creatinine 1.5 mg/dL or higher (Granger et al., NEJM 2011) [3]