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Piperine Piperine has reported for protective effects in cigarette smoke (CS)-induced COPD models, probable treatment through inhibition of neutrophil and macrophage recruitments into lung tissue and inhibition of excessive production of pro-inflammatory mediators, including IL-8, LTB4, TNF-, IL-1, and ROS in the airways (Arora et al

Nat Commun 12:5203 Noch EK, Palma L, Yim I, Bullen N, Barnett D, Walsh A, Bhinder B, Benedetti E, Krumsiek J, Gurvitch J et al (2024) Cysteine induces mitochondrial reductive stress in glioblastoma through hydrogen peroxide production

IFN- and TNF- then activate the STAT1 and nuclear factor B (NF-B) pathways in brain metastatic cells to promote tumour growth and chemoresistance

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