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Below, we summarize four major categories of polyphenolsflavonoids, phenolic acids, stilbenes, and lignanshighlighting representative compounds and their potential roles in PD prevention or therapy

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This relationship is broken by oxidative or electrophilic stressors, which allows Nrf2 to nuclear translocate and attach to antioxidant response molecules (AREs)

Its internal support that reflects externally over time

Looking forward, enhancing the bioavailability and targeted delivery of polyphenols could open new avenues in drug development for metabolic disorders, dermatological applications, and the formation of functional foods aimed at improving physical performance and overall well-being