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MachadoPPSteeleEMLouzadaML da CLevyRBRanganAet al

Freedman R, Hunter SK, Law AJ, et al

2.6.1 Nrf2 signaling Nrf2 is a crucial transcription factor that plays a significant role in preserving mucosal balance by inhibiting the excessive production of ROS in IBD.Nrf2 has a dampening effect on the inflammatory response and the damage to the mucosal lining through its antioxidant actions (87)