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High inducibility of mouse renal CYP2E1 gene by tobacco smoke and its possible effect on DNA single strand breaks

PrymaLab answers all three with documentation rather than claims

Several small molecules identified in a drug screening appear to converge on metal ion chelation and/or inhibition of NF-B and Akt/GSK3 pro-survival signaling pathways To get further insights into the molecular mechanisms involved in the regulation of CBS activity, we screened a set of 2,932 small molecules from the National Cancer Institute, consisting in diverse chemical scaffolds, including natural products and approved oncology drugs

Furthermore, no negative effects were noted with the application of NaBPC157

The statement goes thus: In overweight or trained individuals, it has been shown from most controlled studies that L-carnitine supplementation has no impact on muscle carnitine content, fat metabolism, or weight loss