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Overall, this comprehensive experimental design allowed for the evaluation of Epitalons effects on key aspects of oocyte physiology, including oxidative stress response, mitochondrial function, spindle morphology, and developmental potential

Citrulline rapidly declines in LPS(+ IFN-)-primed BMDMs, and ASS1-mediated citrulline depletion is responsible for JAK2STAT-1 signaling activation and proinflammatory cytokine generation, stimulating the M1 phenotype [280]