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Am J Physiol Endocrinol Metab 296, 256-261 (2009)

By inhibiting NNMT, it leads to an increase in intracellular levels of NAD+ (nicotinamide adenine dinucleotide), a critical coenzyme for cellular metabolism and mitochondrial energy production

[DOI] [PubMed] [Google Scholar] 49.Xu X., Zhang L., He Y., Qi C., Li F

TABLE 1 Overview of the small molecule inhibitors targeting NNMT

In the area of antibody engineering, the therapeutic potential of novel conjugated half-life extended nano-BiKEs (Bispecific Killer-cell Engagers) was evaluated