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Proc Jpn Acad Ser B Phys Biol Sci 86(6), 588-610

You have Von Hippel-Lindau (vHL) Disease: This rare genetic disorder predisposes individuals to blood-vessel tumors

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Because angiogenesis is a defining hallmark of tumor growth and metastatic progression, any therapeutic agent that enhances neovascularization could, in theory, facilitate tumor expansion and promote metastatic dissemination