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LATE DISSEMINATED LYME If symptoms have been present for greater than one year, or if you have received prior therapy for Lyme disease, then other potentially contributing causes such as co-infections, mold, autonomic dysfunction, mitochondrial dysfunction, mast cell activation, and autoimmunity should be explored as part of the differential diagnosis

Impaired mitophagy and fragmented mitochondrial morphology are emerging as novel contributors to neuronal vulnerability in AD (Figure 3)

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(31) demonstrated through precision nutrition research that adjustments in dietary macronutrient proportions can induce significant changes in gut microbiota composition within days, providing a theoretical foundation for improving metabolic health through dietary intervention