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10.1016/j.expneurol.2004.01.018 Exp

Proc Natl Acad Sci USA 110(30):1247412479

Con el fin de comprobar la hiptesis de la probable produccin de TMAO a partir de nutrientes que contienen TMA, los ratones fueron alimentados con alta carga de L-carnitina y varios taxones bacterianos, incluyendo Anaeroplasma y Porphyromonadaceae, comprobando de esta forma que los cambios en las concentraciones de TMAO estaban vinculados con la ingesta de L-carnitina38

This leads to increased production of reactive oxygen species (ROS) and activation of the NLRP3 (NOD-, LRR and pyrin domain-containing protein 3) inflammasome