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ASMBS B12 Recommendations for People after Bariatric Surgery The American Society for Metabolic and Bariatric Surgery has B12 recommendations for patients after bariatric surgery (Parrott, 2017): 350 to 500 g per day if taken orally

Most of what we know to date comes from a mix of preclinical research and the biological mechanisms each therapy targets

The compound was never approved as a pharmaceutical treatment for obesity because the Phase 2 clinical trial results, while showing safety and modest efficacy, did not meet the threshold for drug registration