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Quickstart Highlights MOTS-c is a 16-amino-acid mitochondrial-derived peptide (a short peptide encoded within mitochondrial DNA) that helps regulate metabolic homeostasis, mainly by activating the AMPK energy-sensing pathway [1] [2]

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Combined use demonstrates improved outcomes in animal research, including: Faster formation of granulation tissue and wound closure Reduced edema and inflammation Enhanced tendon-to-bone integration and ligament tensile strength Systemic protection of organs such as liver and kidney in ischemia-reperfusion models Systematic reviews of over 35 preclinical studies consistently report positive histological and functional results, with no observed toxicity