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However, future research must overcome significant methodological challenges, including the lack of standardised diagnostic criteria for brain fog and the need for rigorous, large-scale randomised controlled trials

Nature (1991) 350:564

In recent years, plantderived bioactive compounds have gained attention as potential alternatives or adjunct therapies to levodopa due to their neuroprotective, antioxidant, and antiinflammatory properties [14, 15]