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Physiological concentration of zinc inhibits the production of reactive oxygen species, such as superoxide anion (O), hydrogen peroxide (H 2 O 2 ), and radical hydroxyl (OH) [48] as well as reactive nitrogen species including peroxynitrite (Fig

Its pathogenesis is not attributable to a single factor but is the result of a complex and dynamic interaction among genetic predispositions, environmental stimuli, and immune dysregulation, each of which contributes to initiating and perpetuating the disease cascade

Novel molecular regulators of microglial ferroptosis are continually being identified

A 2015 study showed that lower PTC concentrations were associated with lower memory and cognitive performance

doi: 10.1002/smll.200901158