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The limitations of this work are that we included RCTs, non-RCTs, and observational studies, which may lower the overall quality of evidence of the included studies

Abbreviations: ODB

These supplements come in the form of oral supplements and injections

Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang W-J, et al

Ipamorelin is a selective growth hormone secretagogue frequently investigated for its interaction with growth hormone secretagogue receptors (GHSR) and ghrelin-associated signaling pathways