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Acknowledgments This work was supported by the Core Facility of Basic Medical Sciences, Shanghai Jiao Tong University School of Medicine

The quality check and trimming of sequences were done as described earlier

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Naturally, the production of AFs may exert selective pressure on exposed arthropods to evolve resistance or tolerance mechanisms that can manifest in detoxification mechanisms or active antagonism towards the fungus

Antioxidants such as N-acetylcysteine, mitochondrial-targeted ROS modulators, and superoxide dismutase mimetics show protective effects in preclinical models, but clinical validation is limited