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The primary source of free heme is hemoglobin derived from senescent red blood cells, and heme metabolism takes place in all mammalian cells (Figure 1)

It also regulates caspase-3 and Bcl-2 proteins to protect neurons from glutamate toxicity, thereby reducing the risk of ischemic stroke and brain damage [22]

These antibodies are invaluable for detecting, quantifying, and localizing proteins in complex biological samples

postulated that individuals with lower GPx activity are predisposed to impaired antioxidant protection, which leads to oxidative damage to membrane fatty acid s and functional proteins (Fig