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Arauz, J., Ramos-Tovar, E

A number of recombinant strategies have been developed to synthesize bispecific antibodies (BsAbs), which include single chain variable fragment (scFv)-derived formats such as diabodies, tandem diabodies, BiTEs (bispecific T-cell engager), and DARTs (Dual Affinity Re-Targeting), as well as immunoglo-bulin G (IgG)-based formats such as Triomab, DVD-Ig (Dual Variable Domain antibodies), and two-in-one antibodies 14

This process is further catalysed by the action of mitochondrial glutamine dehydrogenase (GDH), resulting in the conversion to -ketoglutarate (-KG)

Fatigue/low energy Weakness Numbness and tingling in the hands and feet Cognitive impairment (most commonly seen in the elderly population) A significant deficiency can cause nerve damage The complicated absorption of vitamin B12 B12 is bound to protein in food and must be released in the stomach with the help of HCL (stomach acid) and pepsin