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Model: Female US NIH National Institute on Aging (NIA) Aged Rodent Colony mice aged 22 months Dosage: 10 mg/kg of 5-amino-1MQ administered with subcutaneous injections for eight weeks

It used a ShapiroWilk test to assess normality and an F-test to assess homoscedasticity, and attempted log-transformation to resolve any lack thereof 40

Assay Development: Using the fragment as a reference standard to calibrate equipment or validate new in-vitro testing methodologies